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Characteristics of major depressive disorder according to family history of depression : A CRESCEND-K (Clinical Research Center for Depression in Korea) study.
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Seunghee Jeong, Hyeon Woo Yim, Youngeun Jung, Sunjin Jo, Taeyoun Jun, Sung Won Jung, Minsoo Lee, Jaemin Kim
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Korean J Epidemiol. 2008;30(2):272-280. Published online December 31, 2008
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DOI: https://doi.org/10.4178/kje.2008.30.2.272
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Abstract
PURPOSE
People with a family history of mood disorder are more likely to have depression. This study compared the characteristics of non-psychotic major depression disorder according to family history of depression.
METHOD Subjects were total of 817 persons recruited for the CRESCEND-K multicenter trial. Characteristics of depression and suicide history of patients with and without a family history of depression were assessed. Family history was determined through self-report.
RESULTS Of 817 participants, 12.4% had a positive family history of depression. Those with family history of depression reported an earlier age at onset of MDD, and more psychiatric comorbidity. Severity of depression and anxiety were not different according to family history of depression. There were no difference in attempted suicide history, number of attempted suicide and age at onset of 1st attempted suicide according to such a family history.
CONCLUSION Patients with family history of depression reported earlier onset of MDD and more history of psychiatric comorbidity.
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Summary
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Citations
Citations to this article as recorded by  - The Associations between Social Support, Health-Related Behaviors, Socioeconomic Status and Depression in Medical Students
Yoolwon Jeong, Jin Young Kim, Jae Seon Ryu, Ko eun Lee, Eun Hee Ha, Hyesook Park
Epidemiology and Health.2010; 32: e2010009. CrossRef
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